BindingDB PrimarySearch

Found 2 of ic50 data for complexid = 50000830

HLA class II histocompatibility antigen gamma chain/Proto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

BDBM50018830(CHEMBL3286830 | US10543199, Compound PF-06463922 |...)

IC50: 0.230nMAssay Description:Inhibition of CD74-ROS1 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair

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HLA class II histocompatibility antigen gamma chain/Proto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

BDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)

IC50: 3.90nMAssay Description:Inhibition of CD74-ROS1 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

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3D Structure (crystal)